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Elucidating human phosphatase substrate networks plus

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Targeting cyclin-dependent kinases for the treatment of pulmonary arterial hypertension

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The interplay of UV and cutaneous papillomavirus infection in skin cancer development

Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Help us improve our products. Sign up to take part. A Nature Research Journal.
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EMBL - European Molecular Biology Laboratory

PhD , University of Basel. Mol Cell 73 6 doi: Pigment Cell Melanoma Res 32 1 doi: The von Willebrand factor Tyr allele is a gain-of-function variant and a risk factor for early myocardial infarction. Blood 4 doi:
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Upon activation of protein kinase A PKA , perilipin 1A is phosphorylated and CGI rapidly disperses into the cytoplasm, enabling lipase coactivation. Moreover, Ser was not required for CGI function to increase triacylglycerol turnover in human neutral lipid storage disorder fibroblasts that lack endogenous CGI Perilipin phosphorylation also contributed to CGI dispersion. The control of lipolysis in adipocytes of vertebrates is a carefully orchestrated process. The enzymes that catalyze triacylglycerol hydrolysis in adipocytes include adipose triglyceride lipase ATGL , hormone-sensitive lipase, and monoacylglycerol lipase, to cleave the first, second, and third ester bonds, respectively 1 — 4.

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